Researcher Spotlight – Zoltan Szallasi, MD

Defects in DNA repair pathways are an underlying cause of the development and progression of breast cancer, and these defects often determine how a patient will respond to particular therapies. PFP-funded researcher, Dr. Zoltan Szallasi from Boston Children’s Hospital, is developing methods of identifying breast cancers with alterations in the DNA repair pathway—an advance that is crucial for determining which patients will benefit from PARP inhibitors, a class of drugs that has been successful in treating those whose tumors harbor these defects.  For additional details, go to